Inclusion Body Myositis Foundation

897 Washington Street, #600005

Newton, MA 02460

mail@ibmfoundation.org

Resources

IBM Clinical Trials

A listing of previous and ongoing IBM clinical trials:

Therapeutic

ClinicalTrials gov Identifier

Year

PubMed ID

N

Dur months

Placebo Controlled

Outcome Measures

Published

 

 

 

 

 

 

 

AZA + MTX

 

1993

8393509

11

3-6

No

Strength

IVIG

 

1993

8492940

4

2

No

Strength

IVIG

 

1994

8058161

9

 

No

MMT/Disability

Prednisone

 

1995

7617187

8

6-12

No

Decline

IVIG

 

1997

9065553

19

6

Yes

QMT/MMT

IVIG

 

2000

10701893

22

12

Yes

MMT/NSS

IVIG+prednisone

 

2001

11171896

37

3

Yes

QMT/MMT

IFN-beta-1A-low

 

2001

11706093

30

6

Yes

QMT/MMT

MTX

 

2002

11891832

44

11

Yes

QMT/MMT

Oxandrolone

 

2002

11940697

19

6

Yes

QMT/MMT

MTX+ATL vs MTX

 

2003

12874415

11

12

No

Myometry

IFN-beta-1A-high

 

2004

15326251

30

6

Yes

QMT/MMT

Etanercept

 

2006

16432140

9

17

No

QMT

Alemtuzumab

NCT00079768

2009

19454532

19892769

13

12

No

QMT/MMT/QST

Unpublished

 

 

 

 

 

 

 

Lithium

NCT00917956

-

 

-

 

 

 

In Progress

 

 

 

 

 

 

 

Etanercept

NCT00802815

-

 

-

12

Yes

QMT/MMT

Arimoclomol

NCT00769860

-

 

-

4

Yes

QMT/MMT/QST

BYM338

NCT01423110

Novartis Link

-

 

12

2

Yes

MRI Thigh volume

Dur=duration; AZA=azathioprine; MTX=methotrexate; IVIG= intravenous immunoglobulin; IFN=interferon; ATL=anti-T lymphocyte globulin

QMT=quantitative muscle testing; MMT=manual muscle testing; NSS = neuromuscular symptom score; QST=questionnaire